Monday, March 11, 2024

Single particle analysis enabled by 25 second transient times!



Okay....y'all. Are you ready for ABSOLUTE SINGLE MOLECULE SENSITIVITY?

Are you willing to accept 2 SCANS/MINUTE to get it?

No?!?!? 

Why? Oh. You have multiple studies you'd like to complete before you retire? 

Well.....crap....here it is anyway! 


Look, there isn't enough helium left on earth for unimportant things like cooling large magnetic drivn FTMS systems which...could...well.... do this...ummm....same thing....?...at higher resolution and 50x faster....? We need the remaining helium on earth for MRI scanners, which are actually important. Now....how the "Everything costs $1" store my kid loves can seemingly fill seven thousand Helium balloons a day...for $1....is still a complete and total mystery to me. 

Obviously, measuring a "single-ion" of anything is really really cool and not everyone's first motivation is how many chromatographic peaks across a scan they can get. Honestly, the most impressive part is probably the fact that "singe ion" didn't degrade in 25 seconds while making 400 zillion rotations around the inside of that little tiny vacuum chamber! 

1 comment:

  1. Always nice to hear your take on it. My gut feeling is that we can store them even much longer if our electronic boards were more stable

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