Would it be worth borrowing some tools from one of these other fields for -- a 45% increase in intact protein identifications?!?!?
Considering how many people in our field will drop $1M for a 20% increase in IDs, I'd say this is worth taking a look at. And - you don't even have to - it looks like you can just upgrade MetaMorpheus and run some topdown proteomics through it (good benchmark dataset here) and just use the new "averaging with rejection" feature.
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