This stats heavy paper takes a look at serum proteome changes correlated with different negative effects of getting older in a population of men 64 and older.
Stats are ridiculously critical when you're looking at so many variables.
...how are you tossing these awesome outliers...?
I'm not qualified to really evaluate the downstream interpretation, but it seems solid and thoughtful. The upstream, however, was performed by depletion columns and using one of those giant Agilent time of flight instruments that have the ion mobility cell in the middle and the depth of coverage looks solid.
I'm assuming they'll follow up with an analysis of elderly females shortly.
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