(Re?) evaluating MS1 quan algorithms!

WHOA.

Check this new paper out of Smith (Montanta) lab!

Why?

1) Here is the equation for how MaxQuant extracts peaks for quan
2) Here is the equation for how OpenMS extracts peaks for quan

Here is how they perform on a relatively simple standard that someone spent 10,000 hours(???) profiling in it's exhaustive entirety....

Now we have a new way to test any label free algorithm!!