Thursday, April 29, 2021

Theoretical considerations of "next generation" proteomics!

 Now for something completely different....

Non mass-spec based proteomics is coming, or is here already. It's not going to be perfect, but LCMS proteomics isn't either.

Magnus discusses two such technologies and presents some surprising results. A high number of canonical human proteins can be identified with knowing the correct sequence of just 3 amino acids. Of course, the canonical human proteins are only part of the story but a lot of LCMS proteomics only considers those sequences, making it a fair comparison. 

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