Now that we've got multiple instruments breaking the 100 scans/second limit, we're starting to see some promising old ideas coming back. One is the data independent acquisition (DIA, or in this case, the trademarked "SWATH") running with isolation widths we'd normally see for data DEpendent (DDA). To get enough scans across the peak, this group compromised a little on their mass range limit but sees improvements in peptides/proteins and %CVs in a 2 proteome digest standard.
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