So....this used to be Clostridium, but it is called something else now that starts with a C. that shouldn't confuse anyone, since it is still C.diff.?
Regardless of the name it is still (one of?) the leading cause of hospital acquired infections. Go in for something else, possibly get C. diff.
Here is a great study on this awful giant bacteria's phosphoproteome!
These authors weren't even content with just doing phosphoproteomics (Q Exactive HF after Titanium Dioxide bead based enrichment) -- they also used/constructed mutant strains and analyzed those.
Lots to unpack here, including a better understanding of how an important pathogen goes into sporulation (which makes it resistant to most things you'd use to clean a hospital). And -- the unusual use of S/T phosphorylation sites. In school back when I went it was very clear bacteria used different sites, but that's what we're here for. Fixing textbooks and finding out ways to kill bacteria hanging out in hospitals.
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