Tuesday, March 8, 2022

BOOST your phosphoproteomics without enrichment!


I'm going to just leave this here because the abstract graphic explains what this team is doing. Why enrich every sample? Enrich one, use that as a "Boost" channel at a slightly higher level so that is the dominant ion selected for fragmentions. Violin! You've effectively phosphoenriched all of your multiplexed samples. 

I will also go so far as to say that this works great in our hands here and I might consider a confirmatory study even. 

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