Friday, February 10, 2017

Finally! LOD for Q Exactive Classic peptide PRM in a complex matrix!

I'm embarrassed...cause I know some of these authors on this poster...and it is from HUPO 2012... but I have been looking for info like this here and there for months.

What is the limit of detection (LOD) and limit of quantification (LOQ) for the QE running PRM mode (used to be called targeted-HCD) -- in a complex matrix?

The answer is here -- in this case, heavy peptides spiked into an E.coli background.   Imagine -- much better with the newer stuff -- and...a much better test of LOD/LOQ than the ones we typically see.

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