Proteomics of cardiac xenografts in humans (and preclinical models)!

A few years ago I had abundant optimism that if my heart or liver up and decided it was time to retire I'd be able to pop onto a website and order myself one from a company that spun out of one of the world's best engineering/agricultural universities (go Hokies).  

Then the world's single most pathetic person was allowed to rampage through our regulatory sciences haphazardly firing people....and this is one of many things that have now been set back by years here. 

But it looks like first world countries are still moving forward with patient xenotransplants and here is some serious data. 

It looks like all of the cellular data is single RNA sequencing, almost entirely from nuclei. Which....I'm still really unclear why that is valuable data at all. Like....aren't the important transcripts all leaving the nucleus to be translated? To be fair, 1) This is likely my problem and/or conceptual issue, and 2) I don't understand what value proteomics of a nucleus provides either. 

But there is plasma proteomics! Of primates with hearts grown in non-primates!?!? Totally worth taking a look at.