I legitimately don't know who came up with diagonalPASEF - there were too many cool methods too fast for me to even try them. But it almost looks like 3 groups (all European...of course....) all had very similar ideas. But on my new instrument it's just a button, so Imma just push it and see what happens.
The bummer is that I do have to take my source off and calibrate the instrument with the ESI source - which I haven't done since it was installed - (you can do good mass and TIMS calibration now without the ESI source but you do need to sensitivity tune and/or quad tune for diagonalPASEF with the source).
But this is legitimately smart looking!
Whoa! I went to the new DIA-Neural Network website (Aptila.bio) has anything about support for this mode that I should read and found something I didn't know was publicly shared! Also, not sure yet on whether diagonal is supported, but it does look like I can lie to DIA-NN and say that it is SLICE-PASEF. We'll see!
Y'all, this ASMS is going to be sooooo crazy. Despite the lack of Europeans and the fact none of us in the US have any money to do science.....
No comments:
Post a Comment