Top-down proteomics of Alzheimer's tissues reveals entirely new targets!

 

I've got a lot to do today, but this new study is a jaw-dropper.

Quantitative top down (intact protein!) proteomics. Of over 100 individuals (I think over 1,000 samples?!?!?) and multiple proteoform level alterations that appear differential in Alzheimer's? I will come back to this, but you should absolutely check this out.