Electron capture increases protein stability by 60x - but you'll never get to use it!

 

Heading into ASMS shortly and there will be lots and lots of places where business and science interact. We'll see a load of vendor talks where the two things are clearly working together to make things better... but we'll also see... the other thing.

Case in point - 

An e-Mission EXD cell equipped after the quad on an Orbitrap UHMR can stablize the hell out of large proteins going into the Orbitrap for "single ion" detection (it's not really single ion, it's crappy signal measurements for deconvolution and enough combined to make it deconvolutable and since the mass accuracy is phenomenal it works AND it's way way way more sensitive than any other FTMS based intact protein measurement method - it's brilliant but the method name confuses people a lot). 

You know what it needs? Proteins to be 60x more stable!!! (It's not as much stability as charge reduction but that's enough nerd talk for now!) Want one? 

Too bad! E-mission was acquired! 

Man, they would still sell those products, though, right?