If you've got a nice newer Orbitrap, I believe several of them have the ability to use the phase constraint calculations to enhance the resolution of a tiny section of the MS/MS mass range before...
...this happens to the Raspberry Pi level processor in your instrument. It's just too much algorithm. At ASMS 2020 I saw a poster or maybe 2 talking about linking GPUs up to an Orbitrap to expand the phase constraint range - and now we've got real results to dig through! Is this the return of BoxCar? Maybe? It sure doesn't hurt DIA results to get twice the resolution in the same amount of time!
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