Tuesday, August 28, 2018

You can add Ion Mobility to your Fusion!

*Cue someone to email me and tell me FAIMS and Ion mobility are different.*

high-Field Asymmetric waveform Ion Mobility Spectrometry is back in the form of the FAIMSpro device you can add to any Tribrid mass spec!

What's it do? It allows gas phase selection of peptides directly inline on your instrument.

I took this from the manufacturer's website here -- 24% increase gain when using FAIMS on a Lumos, vs not?  This is ion trap MS/MS, btw, but that is an amazing boost!

Some details I've found between the spec sheet and the press release.

The data can be processing in Proteome Discoverer 2.2 (no digging through GoogleGroups to find the patch to process your data like some other ion mobility medium resolution system we hear a lot about)

FreeStyle can also process the data (might mean you finally have to ditch QualBrowser -- which, honestly, you really should. Yeah, I'm still opening everything in Xcalibur too -- but FreeStyle is so so so much better.)

FAIMs Fusion operational software templates are also ready to go (new Fusion tune upgrade coming?!?)

Skyline can also deal with the data automatically!

If the manufacturer plans to put this device on it's fastest and most sensitive mass spectrometers, I don't see it mentioned anywhere, but it provides an enormous boost for the ones made here in the U.S.!

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