Thursday, April 12, 2018
A standard to test inference algorithms!!!
I absolutely have to run out the door, but I have got to leave this here so I can read it if I ever get caught up again!
Proteomics is great at assigning MS/MS spectra to peptide identifications (Peptide Spectral Match -- PSMs).
We are...not so great...at figuring out what protein that PSM belongs to.
We try really hard and we've got lots of things that do it for us.
As far as I know we've NEVER had a good standard for testing how well that algorithm builds a protein identification out of a PSM. (Sure, we have years of evidence that the things we use work) but this is a standard specifically engineered to help test the efficacy of algorithms!
Check this out here!