Well...this one looks like magic...
I was reading it on my phone yesterday, but I'm reasonably sure this was a custom Nano DESI source equipped on an Orbitrap Fusion 3 (Eclipse) or 4 (Assend).
There are some ridiculously nice pictures in it, but if you're getting spatial localization of large proteins or medium sized protein complexes, there is some impressive mass spec wizardry going on here. Localizing a 185kDa protein in a human kidney??? Whoa. One of two really impressive spatial proteomics papers that dropped this weekend. The other one is in my wheelhouse a bit more and I'll probably get to my notes on it later.
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