This paper out of Benjamin Garcia's lab is the reason we need good accessible data repositories. In the paper from Simone Sidoli et. al., this group looks at the consequences of some derivatization techniques used in histone analysis. Turns out that some of them create unique post-translational modifications. If you didn't know to look for them, you might be missing a ton of your MS/MS assignments.
Now that we do know about them, however, we can go back through datasets generated using these compounds and maybe find cool new stuff!
Thanks @PastelBio for another great read.
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