Tuesday, December 9, 2014
The Holy Grail! Complete integration of proteomics and metabolomics data!
Whoa! Yes, this is a simpler system than a lot of us are using. But we have to pull off this stuff in simpler systems in order to prepare for more complex systems.
In this awesome paper, iTRAQ quantitative proteomics and quantitative metabolomics to a bacterial system that is stressed with a toxic compound. Interestingly, they decided to use a bacteria I'm unfamilar with rather than our normal bacterial workhorses of E. coli and Bacillus subtilis. This paper is a really nice example of using these complementary techniques to build our understanding of a biological event!