Wednesday, September 17, 2025

Is this finally - in cell crosslinking -for real?!?

 


Okay - this has been going on for a while now - you might find 10 posts on this blog about the quest 


of protein-protein intereactions. 

Putting protein crosslinkers in to bind proteins together for proteomic analysis! 

Is this it?!? It looks pretty smart. But I also have a bunch of crap in my freezer that works in a centrifuge tube with 4 proteins (sometimes....) that absolutely does not work in-cell. 


If so, I'm 

(...ugh...you work with what you have when you've got 5 minutes for a blog post and a protein bar...) 

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