An Agilent ESI source that might work?

 

Since this is a proteomics blog you probably aren't aware that Agilent makes mass spectrometers. While most of my commercial dealings with this company by, unit order, is the 5 qPCR/rtPCR instruments that we piled up on a loading dock during the pandemic that kept showing up functional for somewhere between 0 and 60 days - I have gotten hands on time with both Agilent QQQs and QTOFs in the last couple of years. 

The ESI sources these instruments arrive with are....unique... and interesting..... and quite honestly make the nanoESI sources of the early 2000s seem both mature and intelligently engineered. People I know using Agilent QTOFs leave the sources that come with the instruments in the boxes unopened and build their own.

NewOmics is one of those innovative little companies that finds fun little niches in which to operate. They decided "wait, these instruments don't have ESI sources? Let's sell one!"

There is a webinar coming up about it here, but it sounds like you can see them in person at multiple upcoming meetings. 

https://www.newomics.com/lc-ms-webinars/large-scale-targeted-proteomics-using-agilent-6495d-lctq-with-newomics-ion-source/