Most proteomics people don't care what the size of their instrument is. We're all tucked away in the basements of condemned buildings breathing in mold and absestos and we're too busy competing with water than people for space.
However, for fields like point of care diagnostics or field based analysis they're taking tiny little mass specs to the site or to patient bedsides. Compared to the size of an LTQ FT or a 12 foot tall Bruker, our electrospray sources seem to take up negligible space - but they're pretty darned big compared to a single quad.
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