This certainly isn't the first comparison of label free quan algorithms, but it might be one of the most comprehensive and well executed ones.
5 publicly available data sets (all spike-ins of digests into complex backgrounds).
5 common software packages used for all comparisons
Exploration of different imputation methods and how they affect each one of these software package results.
Cool and complex metrics developed and clearly explained (I had to circle each on so I could reference back to it -- and the morning after reading it I can not tell you what a LogFC is without going back to look, but it seemed logical!)
And Open Access! I am surprised to just now notice that it is from last fall?
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