Tuesday, June 9, 2026

Two new preprints on differentiating single cells!

Yo, these are both SO cool. I'm very very jealous. I've been trying to find collaborators who can differentiate out some cells for me for over a year now. 

I'm lumping them together now becaus I'm still trying to dig my inbox out. 

One is cardiomyocytes! 


And they use the AIP! Apparently these can only be obtained in certain countries, btw. In Austria, they'll sell you the upgrade, but you can't get it installed. 

And this one is differentiation out to motor neurons! So cool.


If you were a total jerk you could point out that this is differentiating big cells out to massive cells so there is a lot to work with (respectively) in both cases. If you were someone who does work in liver cells - which are also gigantic and have exceptionally friendly copy number distributions (600-ish proteins make up like 85% of the hepatocyte proteome and they're probably the proteins you care about in the liver), it would be better to delete this whole paragraph. Or....try to insert a GIF from a Mac and fail again! 



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