Maybe this was here before? I'm not going to look, but it's definitely out now in JPR.
It makes sense in my head, though. The same way that a single population of a million ions ionized at the exact same second might end up being distributed between mostly +2 charged, some +3 and maybe a barely detectable number of +4. Why wouldn't that population of peptides dissolved in acidic buffer also have 2 different possible shapes (or more?) Is that charge linked in some way? Would make sense. The authors suggest a simple calculator for predicting both modes - which would be amazing - but it doesn't appear to be in the Github. https://github.com/cox-labs/CCS - maybe it's coming? Or maybe I don't have nearly enough time today and all the maths in the paper scared me a little? Probably.
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