Sunday, April 12, 2026

DIA-NN 2.5! Now with 70% more ....70%?? ...more peptides!?!?

 

Okay, we have to take a look at this for real. I do like the color scheme on these plots, though...

As an aside, I ran a commercial program for some people recently and it gave me 20% more protein groups than the ones I currently use. Those extra 20% really annoyed my collaborators. They were ...like... biologically very very unlikely...? Not DIA-NN, a commercial thing, but I did re-learn a lesson that more peptides isn't always a better. But DIA-NN has built enough credibility for me to be hesitantly optimistic that I will like this new version. 

Get it where you get DIA-NN! Probably here https://github.com/vdemichev/diann

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