Friday, June 20, 2025

You can fix cells and then ship them out for single cell proteomics! Here are the best ways!


This isn't the first study of it's type but this digs into more variations of how to fix cells. 

Something everyone doing single cell proteomics (SCP) has struggled with is HOW TO GET THE FREAKING CELLS TO THE MASS SPEC LAB.

At ASMS, I detailed my adventures preparing EvoTips and driving them across the completely insane and poorly maintained Pennsylvania Turnpike. In case you were wondering - I have far better luck keeping the tips at a stable temperature and being on wet ice seemed to be a detriment to the tips. n=1.

Meh. I was typing about something....THIS!


Okay, so there are obviously reasons why you might not want to put formaldehyde or something on your cells, but if there aren't, this may open the door up to all sorts of new collaborators! 

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