Phosphorylation sites that alter thermal protein stability.....

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And another great example?!?  Phosphopeptides that alter protein thermo-stability? And their bulk identification?

The biggest advance for us with all these recent studies is that these techniques are starting to seem a whole lot less daunting from a sample prep and execution standpoint. And, if you look at the results from the earliest studies to these newer ones, the advances in the chromatography and mass spec hardware really illustrates how far we've come. Now we're (well...some people in Seattle rumored to be talented are...localizing the exact phosphorylation sites that are causing structural shifts in protein 3D structure enough to affect something as primary as thermal changes? 

!!! Wait!! This isn't even the only study THIS WEEK!!  Here is the second one.