Is your awesome new instrument generating so much data that you can't process it fast anymore? My data density has jumped about 5x from my last hardware to my new stuff and the data processing is correspondingly less faster.
A huge thank you to the Director of Proteomic Innovation at Cedar Sinai, Dr. Simion Kreimer for texting me about this new thing called InfinDIA (which is in a free [demo?] for academics in DIA-NN 2.3 that you can get and read about here.
I stole one page of the important stuff!
How much faster are we talking about? One pseudo-bulk run (25 cells) on DIA-NN 2.2 was running about 25 min/file to process with our previous settings on our admittedly underpowered Dell Craputer with the Ultra 9 285 and 128GB of RAM (running 20 threads so there's still enough power left to remote login to the box)
When toggling the mode to InfinDIA in DIA-NN 2.3 it appears to have completed 6 files with MBR in about the same amount of time! This is just a single run and should be re-checked to see what other changes happen, but it's definitely seems worth taking a look at, cause...
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