Wednesday, October 30, 2024

msqrob2PTM - Normalize PTM data against global proteomics to actually find the important PTMs!

If you take this great new paper and print out any figure you could approach any scientist on earth from a long distance holding it up. As soon as they could see it at all, they'd know - everything in this paper is written in R. Which is totally cool, I'm not making fun. It's just the most R'y proteomics paper I've opened in a while. 


What is it? It's a statistically valid way of taking your PTM level peptide data and normalizing it against your whole protein data, so you can get stuff like relative phospho-site occupancy per molecule. Great for those biologists who expect this to be the standard output in a PTM study. 

1 comment:

  1. Came out as a preprint back in December of last year - need to follow my X (twitter) feed a bit more closely :-)

    ReplyDelete