Thursday, March 7, 2013

In depth profiling of the human placenta proteome

In yet another amazing paper out of our friends at the human proteome project, this new paper from HJ Lee et al., describes the comprehensive proteomic mapping of the human placental proteome.  Maybe we overuse the word "comprehensive" sometimes.  I'm not doing that here.  These proteins were fractionated by SCX, HILIC, and OFF-GEL.  They were isobarically tagged.  They were enriched for phosphopeptides and they were enriched for glycopeptides and on and on.  The result is the most comprehensive look at the human placenta that has ever been assembled.  The breadth of this work is just fantastic!

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