Thursday, May 6, 2021

The COV-MS paper is out! Details of the community developed SARS-CoV-2 LCMS Assay!

It was super cool being on the outside and watching this awesome resource come together from this multinational team. Of course, the first priority was getting assays live and the final paper was something to get out later., but it's finally here. It's such an interesting read! 100% recommended, even if you burnt out on COVID papers 11 months ago. 

I'd personally like to thank these 100 authors for the shoutout for our team's preprints even if they are pointing out that our models were far too strict. There just was no precedence for a virus that produces proteins at these concentrations in humans. Some peptides we predicted couldn't be used due to background interference from human or from the human microbiome ended up being great markers because SARS-CoV-2 makes such a high concentration of them! 

Super cool work and I hope this is a precedence for what the LCMS community can do when working together, rather than a once-in-a-lifetime occurrence brought on by an event that will never happen again! 

1 comment:

  1. Hi Ben, Thanks for your post!! To be honest: Thanks to your teams preprint, I was able to convince my supervisor to start working on SARS-CoV-2.