In a nutshell, the paper describes their attempts at using long (up to 2 meter!!!!!) columns to separate and identify complex peptide samples. If you are thinking 1 million PSI backpressure, you aren't alone. They build a custom column heater to keep the backpressure down. And it works. Holy cow. In a 480 minute run they cover 68% of the proteins that they found in the multistage fractionation of yeast extract that they did a few years ago. 68% in 480 minutes.
The kicker here? Call up your nanospray column manufacturer and ask for a quote on a column even 40cm long! Lets see if you get as discouraged as I did. If you know of a company that makes custom columns of this length for less than the price of a Porsche 951, definitely let me know!