I've done a decent amount of rambling about how cool different chemoproteomic strategies are. Here is a good ramble.
Drugs have to do something biologically, right? Since everything biologically has something to do with proteins, chances are drugs interact with them. Chemoproteomics gives us a chance of figuring out exactly whom, where and what.
The argument here is that you lose a lot of information with the normal controlled digestions and limited proteolysis can help. However...whew...your day doesn't get easier from the data analysis side following a limited proteolysis. It's tough to do that with a single purified protein!
Time for an artificial learning machine intelligence thingy!
No comments:
Post a Comment