Sunday, June 5, 2016
Genome level tumor proteome characterization!
WHOA!!! Great talk and its from this ridiculously great paper in Nature Cancer from S Tyanova et al., that you can find here!
Application of SUPER SILAC to a huge cohort of tumors and the application of beautiful levels of statistical analyses to flush out the differences between these tumor types.
Observations found and validated that did NOT appear quantitatively disregulated at the transcript level. (Though a bunch that did! Don't think I'm giving up on the power of RNA Seq just yet, just enforcing the fact that they are both necessary to get a real picture.)
Back to the beautiful statistics! New algorithms implemented into Perseus...which means its currently outside of my capabilities, but...so...powerful...that..I..may...have...to...try....