Thursday, July 25, 2013
Transfect individual cells on a chip!
This advance is getting a lot of exposure. It was featured in this month's "The Scientist" and "Lab Manager" and is getting circulated through the interwebs...because it is awesome.
These tiny microchannels force the cell memberane to elongate, disrupting its ability to maintain homeostasis just long enough that you can get your plasmid or whatever into them. Talk about easy mutations! Probably won't work on anything with a cell wall, peptidoglycan or otherwise, they'll probably just clog the channel instead of stretching. Still amazing.
You can read more about it at Lab Manager here.